Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897981 | 0.85 | RAB9A (0.65) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL400890 | 0.84 | RAB9A (0.77) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL12324391 | 0.82 | RAB9A (0.82) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL5464442 | 0.82 | APEX1 (0.52) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL828586 | 0.81 | ALDH1A1 (0.64) | RAB9ANPC1POLBKDM4EALDH1A1 | |
| SCHEMBL8729424 | 0.80 | ALDH1A1 (0.73) | POLBKDM4EMAOAPTGS2ALDH1A1 | |
| SCHEMBL8726690 | 0.80 | MAOA (0.59) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL8726176 | 0.80 | ALDH1A1 (0.73) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL1566720 | 0.79 | ALDH1A1 (0.62) | RAB9ANPC1POLBKDM4EALDH1A1 | |
| SCHEMBL37273 | 0.79 | ALDH1A1 (0.68) | RAB9ANPC1CTDSP1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | claimed |
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | claimed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | claimed |
| CN-115997016-A | Composition comprising nucleic acid nanoparticles having modular functional groups | 西克斯福德生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
| US-7109329-B2 | Neurologically active compounds and compounds with multiple activities | NAFTCHI N ERIC | 2006-09-19 | — | — | US | disclosed |
| EP-1101793-B1 | Heat ageing resistant rubber composition | BRIDGESTONE CORP (JP) | 2006-01-25 | — | — | EP | disclosed |
| CN-1659156-A | Novel guanidinobenzamides | CHIRON CORP (US) | 2005-08-24 | — | — | CN | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| EP-1409468-A2 | GUANIDINOBENZAMIDES AS MC4-R AGONISTS | CHIRON CORPORATION (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | BIGNON ERIC (FR) | 2004-03-04 | — | — | US | disclosed |
| CN-1263528-A | N-triazolyl-2-indolecarboxamides and their use in CCK-A agonists | SANOFI SYNTHELABO (FR) | 2000-08-16 | — | — | CN | disclosed |
| EP-0984960-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 2000-03-15 | — | — | EP | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5849469-A | Process for forming an image using novel magneta couplers for color photography | EASTMAN KODAK COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| WO-1998051686-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 1998-11-19 | — | — | WO | disclosed |
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0576430-A1 | NOVEL MAGENTA COUPLERS FOR COLOUR PHOTOGRAPHY | KODAK LIMITED (GB) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992012464-A1 | NOVEL MAGENTA COUPLERS FOR COLOUR PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1992-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | CCKAR, CCKBR, NPY1R | RAB9A 1127/4885NPC1 1845/4885CTDSP1 3495/4885 |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | ADRB2, ADRB1, CHRNA7 | RAB9A 1141/4885NPC1 372/4885CTDSP1 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.