SCHEMBL872963

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL872303	0.80	TSHR (0.32)	TSHRCHRM2CHRM4CHRM1TBXA2R
	SCHEMBL872040	0.73	—	—
	SCHEMBL873957	0.71	THRB (0.33)	PRKD3PRKCGPRKCBPRKCAPRKCH
	SCHEMBL23418155	0.70	—	—
	SCHEMBL13210313	0.70	LMNA (0.59)	TSHRCHRM2CHRM4CHRM1TBXA2R
	SCHEMBL22056511	0.70	CYP1A2 (0.46)	TSHRCHRM2CHRM4CHRM1TBXA2R
	SCHEMBL26797562	0.70	CYP1A2 (0.46)	TSHRCHRM2CHRM4CHRM1TBXA2R
	SCHEMBL23447754	0.70	LMNA (0.38)	TSHRCHRM2CHRM4CHRM1TBXA2R
	SCHEMBL25099744	0.70	LMNA (0.59)	TSHRCHRM2CHRM4CHRM1TBXA2R
	SCHEMBL26797560	0.70	CYP1A2 (0.46)	TSHRCHRM2CHRM4CHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.