SCHEMBL8729644

SCHEMBL8729644

Cc1ccc(N2CC(C)(C)C(=O)N2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.42
OPRM1 P35372 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 2/20 0.38
HTT P42858 3/20 0.37
HCAR1 Q9BXC0 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH1A1 P00352 7/20 0.36
MAPT P10636 4/20 0.36
ALOX15 P16050 1/20 0.36
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.35
F2 P00734 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17548918 0.81 MAPT (0.39) NPSR1OPRM1SMN1; SMN2GAAHTT
SCHEMBL8735393 0.81 ALOX5 (0.53) OPRM1SMN1; SMN2GAAALDH1A1MAPT
SCHEMBL10606041 0.80 MEN1 (0.36) NPSR1SMN1; SMN2HSD17B10ALDH1A1MAPT
SCHEMBL14557485 0.79 KMT2A (0.34) NPSR1SMN1; SMN2LMNAGAAHTT
SCHEMBL10606044 0.77 MAPT (0.37) SMN1; SMN2LMNAGAAHTTHSD17B10
SCHEMBL5179391 0.77 ALOX5 (0.50) OPRM1SMN1; SMN2LMNAGAAALDH1A1
SCHEMBL8729641 0.75 ADRB1 (0.41) NPSR1OPRM1LMNAHTTHCAR1
SCHEMBL8751387 0.75 ALOX5 (0.56) OPRM1SMN1; SMN2GAAHSD17B10ALDH1A1
SCHEMBL8904250 0.70 GAA (0.39) NPSR1SMN1; SMN2LMNAGAAALDH1A1
SCHEMBL10581683 0.70 ADRA2C (0.38) OPRM1SMN1; SMN2GAAHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5804359-A OPTICAL DENSITY PROVIDED BY SILVER; HIGHER MOLAR RATIO OF REDUCING AGENT TO SILVER HALIDE IN THE FIRST EMULSION LAYER THAN IN THE SECOND, FOR IMPROVED SIGNAL TO NOISE. EASTMAN KODAK COMPANY (US) 1998-09-08 US disclosed
US-5633126-A Films for reproducing digitally stored medical diagnostic images and integrating non-image information EASTMAN KODAK COMPANY (US) 1997-05-27 US disclosed
EP-0014594-B1 PHOTOGRAPHIC IMAGE REVERSAL PROCESS AND PHOTOGRAPHIC ELEMENT FOR USE THEREIN KODAK LIMITED (GB) 1983-07-27 EP disclosed
US-4258117-A ELECTRON TRANSFER AGENT, CROSS-OXIDATION EASTMAN KODAK COMPANY (US) 1981-03-24 US disclosed
EP-0014594-A1 Photographic image reversal process and photographic element for use therein KODAK LIMITED (GB) 1980-08-20 EP disclosed