SCHEMBL8729672

SCHEMBL8729672

C=C(C)C(=O)NCCC(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12199997 0.87 GBA1 (0.30)
SCHEMBL2998940 0.86 CA2 (0.31)
SCHEMBL12199962 0.86 CA2 (0.31)
SCHEMBL21504381 0.84 TGFBR1 (0.33) TGFBR1
SCHEMBL21504350 0.82 MLYCD (0.33) TGFBR1
SCHEMBL16443433 0.80 TGFBR1 (0.33) TGFBR1
SCHEMBL25076167 0.79 KDM4E (0.46)
SCHEMBL163137 0.78 GRM4 (0.33) TGFBR1
SCHEMBL31304716 0.78 SIGMAR1 (0.40) TGFBR1
Hydrochloric Acid SCHEMBL9818683 0.77 GRM4 (0.32) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110242191-A1 INK COMPOSITION, INKJET RECORDING METHOD AND PROCESS FOR PRODUCING MOLDED PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed
EP-0494842-B1 Rigid contact lenses with improved oxygen permeability CIBA GEIGY AG (CH) 1998-04-22 EP disclosed
EP-0494842-A2 Rigid contact lenses with improved oxygen permeability CIBA-GEIGY AG (CH) 1992-07-15 EP disclosed