Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.72 |
| ▸ | MMP2 | P08253 | 1/20 | 0.72 |
| ▸ | MMP13 | P45452 | 1/20 | 0.72 |
| ▸ | MMP14 | P50281 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729720 | 0.85 | MMP1 (0.70) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL8729717 | 0.85 | MMP1 (0.70) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL8727675 | 0.82 | MMP1 (0.64) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL8727681 | 0.82 | MMP1 (0.64) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL8733003 | 0.74 | MAPT (0.65) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL8733001 | 0.74 | MAPT (0.65) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL13446896 | 0.72 | MMP1 (0.73) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL8181735 | 0.68 | AKR1B1 (0.73) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL29214806 | 0.68 | MMP1 (0.67) | MMP1MMP2MMP13MMP14NPC1 | |
| SCHEMBL29214808 | 0.68 | MMP1 (0.67) | MMP1MMP2MMP13MMP14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |