Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.57 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219618 | 0.82 | HSD17B10 (1.00) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7587764 | 0.82 | HSD17B10 (1.00) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6160546 | 0.81 | HSD17B10 (0.97) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| Ammonia Solution, Strong SCHEMBL1764035 | 0.81 | HSD17B10 (0.97) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8729927 | 0.80 | HSD17B10 (0.67) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8729938 | 0.79 | HSD17B10 (0.72) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL5247064 | 0.75 | OPRM1 (0.78) | OPRL1OPRM1OPRD1OPRK1PLD1 | |
| SCHEMBL11932466 | 0.74 | OPRM1 (0.72) | OPRL1OPRM1OPRD1OPRK1SLC6A9 | |
| Ammonia Solution, Strong SCHEMBL8729935 | 0.73 | HSD17B10 (0.74) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL5556794 | 0.72 | HSD17B10 (0.73) | HSD17B10OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |