Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 2/20 | 0.54 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | SDHB | P21912 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779584 | 0.79 | PTGS2 (0.58) | ABCC8KCNJ11L3MBTL1MEN1KMT2A | |
| SCHEMBL17279853 | 0.74 | HPGD (0.45) | L3MBTL1HPGDNPSR1RAB9AHSD17B10 | |
| SCHEMBL13715627 | 0.72 | ABCC8 (0.56) | ABCC8KCNJ11L3MBTL1HPGDNPSR1 | |
| SCHEMBL13715761 | 0.72 | ABCC8 (0.56) | ABCC8KCNJ11L3MBTL1HPGDNPSR1 | |
| SCHEMBL2875560 | 0.72 | ABCC8 (0.56) | ABCC8KCNJ11L3MBTL1HPGDNPSR1 | |
| SCHEMBL12273674 | 0.72 | L3MBTL1 (0.60) | ABCC8KCNJ11L3MBTL1HPGDNPSR1 | |
| SCHEMBL2374709 | 0.72 | ABCC8 (0.56) | ABCC8KCNJ11L3MBTL1HPGDNPSR1 | |
| SCHEMBL6892419 | 0.72 | ABCC8 (0.56) | ABCC8KCNJ11L3MBTL1HPGDNPSR1 | |
| SCHEMBL15715941 | 0.72 | ABCC8 (0.56) | ABCC8KCNJ11L3MBTL1HPGDNPSR1 | |
| SCHEMBL7773326 | 0.71 | LRRK2 (0.68) | ABCC8KCNJ11L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823889-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034846-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1996-11-07 | — | — | WO | disclosed |