Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 2/20 | 0.56 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | GYS1 | P13807 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.42 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514038 | 0.88 | ABCC8 (0.54) | ABCC8KCNJ11MEN1MAPTCNR1 | |
| SCHEMBL22324677 | 0.88 | GYS1 (0.49) | ABCC8KCNJ11MEN1MAPTCNR1 | |
| SCHEMBL6195096 | 0.78 | KDM4E (0.51) | KDM4ELMNAMAP2K4MAPK1MAPK6 | |
| SCHEMBL2374709 | 0.75 | ABCC8 (0.56) | ABCC8KCNJ11MEN1MAPTCNR1 | |
| SCHEMBL2875560 | 0.75 | ABCC8 (0.56) | ABCC8KCNJ11MEN1MAPTCNR1 | |
| SCHEMBL4382163 | 0.75 | RAB9A (0.49) | MEN1KMT2AKDM4ELMNAMAP2K4 | |
| SCHEMBL13715761 | 0.75 | ABCC8 (0.56) | ABCC8KCNJ11MEN1MAPTCNR1 | |
| SCHEMBL12273674 | 0.75 | L3MBTL1 (0.60) | ABCC8KCNJ11MEN1MAPTCNR1 | |
| SCHEMBL5069948 | 0.75 | ALDH1A1 (0.49) | MAPTKDM4ELMNAMAP2K4MAPK1 | |
| SCHEMBL13715627 | 0.75 | ABCC8 (0.56) | ABCC8KCNJ11MEN1MAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501182-A | The trifluoromethyl of 1 substituted-phenyl 5（Difluoromethyl）4 pyrazole carboxylic acid synthetic methods | 中国农业大学 | 2017-12-22 | — | — | CN | disclosed |
| CN-103764140-B | Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases | 韩国化学研究院 | 2017-05-17 | — | — | CN | disclosed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| WO-1999048890-A1 | HERBICIDAL TETRAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |