Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731128 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL254822 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL29048096 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL1420531 | 0.74 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL3236165 | 0.74 | RAB9A (0.50) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL197298 | 0.74 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL16733990 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL2097234 | 0.74 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL10263003 | 0.74 | CA2 (0.41) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL2094518 | 0.73 | CA1 (0.52) | KDM4EALDH1A1HSD17B10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |