SCHEMBL873210

SCHEMBL873210

Cn1c(N)nc(=O)c2ncn([C@@H]3O[C@H](CO)C(O)C3O)c21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.58
▸ GMNN O75496 1/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ TP53 P04637 1/20 0.58
▸ NFKB1 P19838 1/20 0.58
▸ DNMT1 P26358 1/20 0.58
▸ THPO P40225 1/20 0.58
▸ MTOR P42345 1/20 0.58
▸ HTT P42858 1/20 0.58
▸ RAB9A P51151 1/20 0.58
▸ BLM P54132 1/20 0.58
▸ HBB P68871 1/20 0.58
▸ PMP22 Q01453 1/20 0.58
▸ CYP2C19 P33261 1/20 0.53
▸ HPGD P15428 1/20 0.53
▸ ADORA2A P29274 4/20 0.53
▸ ADORA3 P0DMS8 3/20 0.53
▸ ADORA2B P29275 3/20 0.53
▸ ADORA1 P30542 2/20 0.53
▸ DPP4 P27487 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979500 1.00 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL31685335 0.89 ADORA1 (0.48) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL23414481 0.88 LMNA (0.59) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL30852235 0.88 LMNA (0.59) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL8185392 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL21544852 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL6395695 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL8185399 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL27826042 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL6393071 0.87 TP53 (0.58) LMNAGMNNALDH1A1TP53NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019981-A Methods for characterizing tumors 蒙彼利埃大学医疗中心 2024-05-10 — — CN claimed
EP-3863609-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2021-08-18 — — EP claimed
EP-1485395-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS Biota, Inc. (US) 2004-12-15 — — EP claimed
WO-2003072757-A9 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA INC (US) 2004-10-21 — — WO claimed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 — — WO claimed
CN-120082543-A Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2025-06-03 — — CN disclosed
CN-119789852-A Compositions and methods for delivering RNA 再生技术有限责任公司 2025-04-08 — — CN disclosed
CN-119375375-A Method for detecting nucleotide, cap analogue and nucleic acid in vitro transcription product 楷拓生物科技(苏州)有限公司 2025-01-28 — — CN disclosed
CN-110573619-B Nucleic acid products that inhibit TMPRSS6 gene expression and uses thereof 赛伦斯治疗有限责任公司 2024-11-29 — — CN disclosed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 — — CN disclosed
CN-117642421-A Engineered immune cells specifically targeting mesothelin and uses thereof 武田药品工业株式会社 2024-03-01 — — CN disclosed
CN-117396193-A Compositions and methods for delivering RNA 再生技术有限责任公司 2024-01-12 — — CN disclosed
WO-2004044245-A1 OLIGOMERIC COMPOUNDS HAVING MODIFIED BASES FOR BINDING TO ADENINE AND GUANINE AND THEIR USE IN GENE MODULATION ISIS PHARMACEUTICALS, INC. (US) 2004-05-27 — — WO disclosed
EP-1419247-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS Direvo Biotech AG (DE) 2004-05-19 — — EP disclosed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 — — WO disclosed
WO-2003012100-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS DIREVO BIOTECH AG (DE) 2003-02-13 — — WO disclosed
EP-1281757-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids Direvo Biotech AG (DE) 2003-02-05 — — EP disclosed
US-6369040-B1 INCORPORATING A COMPLEMENTARY SEQUENCES FOR HERPES, PAPILLOMA AND OTHER VIRUSES ISIS PHARMACEUTICALS, INC. 2002-04-09 — — US disclosed
US-6060592-A Pyrimidine nucleoside compounds and oligonucleoside compounds containing same ISIS PHARMACEUTICALS, INC. (US) 2000-05-09 — — US disclosed
WO-1995024185-A1 NOVEL PYRIMIDINE NUCLEOSIDES ISIS PHARMACEUTICALS, INC. (US) 1995-09-14 — — WO disclosed
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