SCHEMBL1979500

SCHEMBL1979500

Cn1c(N)nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.58
▸ GMNN O75496 1/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ TP53 P04637 1/20 0.58
▸ NFKB1 P19838 1/20 0.58
▸ DNMT1 P26358 1/20 0.58
▸ THPO P40225 1/20 0.58
▸ MTOR P42345 1/20 0.58
▸ HTT P42858 1/20 0.58
▸ RAB9A P51151 1/20 0.58
▸ BLM P54132 1/20 0.58
▸ HBB P68871 1/20 0.58
▸ PMP22 Q01453 1/20 0.58
▸ CYP2C19 P33261 1/20 0.53
▸ HPGD P15428 1/20 0.53
▸ ADORA2A P29274 4/20 0.53
▸ ADORA3 P0DMS8 3/20 0.53
▸ ADORA2B P29275 3/20 0.53
▸ ADORA1 P30542 2/20 0.53
▸ DPP4 P27487 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873210 1.00 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL31685335 0.89 ADORA1 (0.48) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL23414481 0.88 LMNA (0.59) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL30852235 0.88 LMNA (0.59) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL8185392 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL21544852 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL6395695 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL8185399 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL27826042 0.87 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL6393071 0.87 TP53 (0.58) LMNAGMNNALDH1A1TP53NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019981-A Methods for characterizing tumors 蒙彼利埃大学医疗中心 2024-05-10 — — CN claimed
CN-122060818-A Chemically modified circular RNA molecules, methods of making and uses thereof 上海元码智药生物技术有限公司 2026-05-19 — — CN disclosed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed
CN-120082543-A Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2025-06-03 — — CN disclosed
CN-119789852-A Compositions and methods for delivering RNA 再生技术有限责任公司 2025-04-08 — — CN disclosed
CN-119604304-A Recombinant RNA molecules comprising an untranslated region or a segment encoding spike protein from the Severe acute respiratory coronavirus 2 Omikovia strain 葛兰素史克生物有限公司 2025-03-11 — — CN disclosed
CN-119375375-A Method for detecting nucleotide, cap analogue and nucleic acid in vitro transcription product 楷拓生物科技(苏州)有限公司 2025-01-28 — — CN disclosed
CN-110573619-B Nucleic acid products that inhibit TMPRSS6 gene expression and uses thereof 赛伦斯治疗有限责任公司 2024-11-29 — — CN disclosed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 — — CN disclosed
CN-118019981-A Methods for characterizing tumors 蒙彼利埃大学医疗中心 2024-05-10 — — CN disclosed
US-20050118605-A9 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation ISIS PHARMACEUTICALS, INC. 2005-06-02 — — US disclosed
US-20050037370-A1 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation BAKER BRENDA F (US) 2005-02-17 — — US disclosed
US-20050032069-A1 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation ISIS PHARMACEUTICALS, INC. 2005-02-10 — — US disclosed
WO-2004044245-A1 OLIGOMERIC COMPOUNDS HAVING MODIFIED BASES FOR BINDING TO ADENINE AND GUANINE AND THEIR USE IN GENE MODULATION ISIS PHARMACEUTICALS, INC. (US) 2004-05-27 — — WO disclosed
EP-1419247-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS Direvo Biotech AG (DE) 2004-05-19 — — EP disclosed
WO-2003012100-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS DIREVO BIOTECH AG (DE) 2003-02-13 — — WO disclosed
EP-1281757-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids Direvo Biotech AG (DE) 2003-02-05 — — EP disclosed
US-6369040-B1 INCORPORATING A COMPLEMENTARY SEQUENCES FOR HERPES, PAPILLOMA AND OTHER VIRUSES ISIS PHARMACEUTICALS, INC. 2002-04-09 — — US disclosed
US-6060592-A Pyrimidine nucleoside compounds and oligonucleoside compounds containing same ISIS PHARMACEUTICALS, INC. (US) 2000-05-09 — — US disclosed
WO-1995024185-A1 NOVEL PYRIMIDINE NUCLEOSIDES ISIS PHARMACEUTICALS, INC. (US) 1995-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050037370-A1 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation RNMT, RRBP1, G3BP1 LMNA 1281/4885GMNN 774/4885ALDH1A1 4679/4885
US-20050118605-A9 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation RNMT, RRBP1, G3BP1 LMNA 1281/4885GMNN 774/4885ALDH1A1 4679/4885
US-20050032069-A1 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation RNMT, RRBP1, G3BP1 LMNA 1281/4885GMNN 774/4885ALDH1A1 4679/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 LMNA 240/4885GMNN 3368/4885ALDH1A1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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