Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185399 | 1.00 | LMNA (0.58) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL6395695 | 0.89 | LMNA (0.58) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL23414481 | 0.88 | LMNA (0.59) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL30852235 | 0.88 | LMNA (0.59) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL27826042 | 0.87 | LMNA (0.58) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL6393071 | 0.87 | TP53 (0.58) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL1979500 | 0.87 | LMNA (0.58) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL873210 | 0.87 | LMNA (0.58) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL21544852 | 0.87 | LMNA (0.58) | LMNATP53GMNNALDH1A1NFKB1 | |
| SCHEMBL21437393 | 0.84 | LMNA (0.55) | LMNATP53GMNNALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2023-05-11 | — | — | US | disclosed |
| EP-1058687-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999041268-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | STING1, CGAS, MAVS | LMNA 636/4885TP53 1339/4885GMNN 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.