SCHEMBL873299

SCHEMBL873299

C[C@H](NC(=O)CC(N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 12/20 0.38
▸ REN P00797 1/20 0.38
▸ ECE1 P42892 2/20 0.36
▸ CTSD P07339 1/20 0.35
▸ HRH1 P35367 1/20 0.33
▸ MMP2 P08253 1/20 0.32
▸ MMP7 P09237 1/20 0.32
▸ MMP9 P14780 1/20 0.32
▸ MMP12 P39900 1/20 0.32
▸ MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29165756 0.93 CCKAR (0.36) BACE1MMP2MMP7MMP9MMP12
SCHEMBL28167878 0.89 BACE1 (0.39) BACE1RENECE1CTSDHRH1
SCHEMBL29591626 0.86 BACE1 (0.41) BACE1CTSD
SCHEMBL29630322 0.86 BACE1 (0.41) BACE1CTSD
SCHEMBL873298 0.85 BACE1 (0.36) BACE1RENECE1CTSD
SCHEMBL30192164 0.84 BACE1 (0.36) BACE1ECE1CTSD
SCHEMBL31073567 0.84 BACE1 (0.42) BACE1CTSDMMP2MMP7MMP9
SCHEMBL30360293 0.83 ECE1 (0.41) BACE1ECE1
SCHEMBL29630564 0.83 SLC15A2 (0.43) RENECE1MMP2MMP7MMP9
SCHEMBL29429284 0.83 SLC15A2 (0.40) ECE1MMP2MMP7MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10758490-B2 Nanocapsules containing microemulsions LIPOTEC, S.A. (ES) 2020-09-01 — — US claimed
EP-4340807-B1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MAT INC (US) 2026-01-28 — — EP disclosed
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-08-01 — — US disclosed
EP-4340807-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS Lubrizol Advanced Materials, Inc. (US) 2024-03-27 — — EP disclosed
WO-2022245758-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2022-11-24 — — WO disclosed
US-11478412-B2 Hair modification composition and method therefor LUBRIZOL ADVANCED MATERIALS, INC. (US) 2022-10-25 — — US disclosed
EP-3212688-B1 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES LUBRIZOL ADVANCED MAT INC (US) 2022-04-13 — — EP disclosed
US-20210154120-A1 HAIR MODIFICATION COMPOSITION AND METHOD THEREFOR LUBRIZOL ADVANCED MATERIALS, INC. (US) 2021-05-27 — — US disclosed
CN-107108837-B Thermoplastic polyurethane films for delivering active agents to skin surfaces 路博润先进材料公司 2021-04-13 — — CN disclosed
EP-3773458-A1 HAIR MODIFICATION COMPOSITION AND METHOD THEREFOR Lubrizol Advanced Materials, Inc. (US) 2021-02-17 — — EP disclosed
EP-2618926-B1 NANOCAPSULES CONTAINING MICROEMULSIONS LIPOTEC SA (ES) 2019-05-08 — — EP disclosed
US-20180311358-A1 THERMOFORMABLE DUAL NETWORK HYDROGEL COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. 2018-11-01 — — US disclosed
EP-3371238-A1 THERMOFORMABLE DUAL NETWORK HYDROGEL COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2018-09-12 — — EP disclosed
US-20170319462-A1 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES LUBRIZOL ADVANCED MATERIALS, INC. 2017-11-09 — — US disclosed
EP-3212688-A2 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES Lubrizol Advanced Materials, Inc. (US) 2017-09-06 — — EP disclosed
WO-2017079248-A1 THERMOFORMABLE DUAL NETWORK HYDROGEL COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-05-11 — — WO disclosed
WO-2016069396-A2 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-05-06 — — WO disclosed
US-20130216596-A1 NANOCAPSULES CONTAINING MICROEMULSIONS LIPOTEC, S.A. (ES) 2013-08-22 — — US disclosed
EP-2618926-A2 NANOCAPSULES CONTAINING MICROEMULSIONS Lipotec, S.A. (ES) 2013-07-31 — — EP disclosed
WO-2012038061-A2 NANOCAPSULES CONTAINING MICROEMULSIONS LIPOTEC, S.A. (ES) 2012-03-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11478412-B2 Hair modification composition and method therefor DSC1, HADHB, PHOSPHO1 BACE1 1365/4885REN 4159/4885ECE1 4596/4885
US-20210154120-A1 HAIR MODIFICATION COMPOSITION AND METHOD THEREFOR DSC1, HADHB, PHOSPHO1 BACE1 1365/4885REN 4159/4885ECE1 4596/4885
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS TYR, DOT1L, CUTA BACE1 3874/4885REN 691/4885ECE1 3739/4885
US-20180311358-A1 THERMOFORMABLE DUAL NETWORK HYDROGEL COMPOSITIONS HSF1, DUOX2, HSPA2 BACE1 4752/4885REN 4616/4885ECE1 3951/4885
US-20170319462-A1 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES DNER, CUTA, PUF60 BACE1 3091/4885REN 4686/4885ECE1 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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