Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.43 |
| ▸ | RELA | Q04206 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733093 | 1.00 | NFE2L2 (0.43) | NFE2L2RELACYP19A1APPACHE | |
| SCHEMBL8734119 | 0.92 | NFE2L2 (0.44) | NFE2L2RELACYP19A1APPACHE | |
| SCHEMBL8734121 | 0.92 | NFE2L2 (0.44) | NFE2L2RELACYP19A1APPACHE | |
| SCHEMBL8733085 | 0.90 | NFE2L2 (0.50) | NFE2L2RELACYP19A1TUBB1MAOA | |
| SCHEMBL8733083 | 0.90 | NFE2L2 (0.50) | NFE2L2RELACYP19A1TUBB1MAOA | |
| SCHEMBL13636781 | 0.85 | APP (0.46) | NFE2L2RELACYP19A1APPTUBB1 | |
| SCHEMBL8734102 | 0.83 | RELA (0.50) | NFE2L2RELACYP19A1TUBB1MAOA | |
| SCHEMBL29794003 | 0.83 | RELA (0.50) | NFE2L2RELACYP19A1TUBB1MAOA | |
| SCHEMBL8734104 | 0.83 | RELA (0.50) | NFE2L2RELACYP19A1TUBB1MAOA | |
| SCHEMBL8733104 | 0.82 | NR1H2 (0.39) | NFE2L2RELACYP19A1APPMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5587445-A | Highly oxygen-permeable heat-resistant material | MENICON CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |