Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733083 | 1.00 | NFE2L2 (0.50) | NFE2L2CYP19A1MAOAMAOBALDH1A1 | |
| SCHEMBL8734121 | 0.94 | NFE2L2 (0.44) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL8734119 | 0.94 | NFE2L2 (0.44) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL8733093 | 0.90 | NFE2L2 (0.43) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL8733095 | 0.90 | NFE2L2 (0.43) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL13636781 | 0.83 | APP (0.46) | NFE2L2CYP19A1RELATUBB1MEN1 | |
| SCHEMBL8766999 | 0.83 | ACHE (0.37) | NFE2L2CYP19A1MAOAMAOBALDH1A1 | |
| SCHEMBL8347751 | 0.83 | TTR (0.54) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL8734102 | 0.80 | RELA (0.50) | NFE2L2CYP19A1MAOAMAOBALDH1A1 | |
| SCHEMBL29794003 | 0.80 | RELA (0.50) | NFE2L2CYP19A1MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5587445-A | Highly oxygen-permeable heat-resistant material | MENICON CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |