Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733109 | 1.00 | HCAR2 (0.37) | HCAR2HTTSMN1; SMN2NPC1GAA | |
| SCHEMBL8733111 | 0.94 | THRA (0.35) | SMN1; SMN2ATMGRM2GRM3LMNA | |
| SCHEMBL3248628 | 0.81 | THRA (0.44) | SMN1; SMN2ATMGRM2GRM3LMNA | |
| SCHEMBL12895143 | 0.76 | GAA (0.36) | SMN1; SMN2GAAATMGRM2GRM3 | |
| SCHEMBL7778356 | 0.76 | HCAR2 (0.38) | HCAR2ATM | |
| SCHEMBL7778355 | 0.76 | HCAR2 (0.38) | HCAR2ATM | |
| SCHEMBL9576255 | 0.76 | HTT (0.33) | HTTSMN1; SMN2NPC1GAAGRM2 | |
| SCHEMBL31190307 | 0.76 | HTT (0.40) | HCAR2HTTSMN1; SMN2NPC1GAA | |
| SCHEMBL9227258 | 0.75 | ALOX5 (0.39) | ATMGRM2GRM3MEN1MAPT | |
| SCHEMBL27353237 | 0.74 | GAA (0.38) | SMN1; SMN2GAAATMGRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63271411-A | — | — | None | — | — | JP | disclosed |
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |
| EP-0524557-B1 | Ocular lens material | MENICON CO LTD (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5391591-A | A curable additional copolymer molding materials having a styrenic monomer, a hydrophilic acrylamide monomer and a crosslinkable vinylbenzyl acrylate monomer; permselectivity, tensile strength, low water absorption | MENICON CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5250583-A | Polymer of fluoroalkyl silicon-containing alkyl fumarate, N-vinyllactam, acrylic or methacrylic acid, crosslinkable monomer | MENICON CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0524557-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1993-01-27 | — | — | EP | disclosed |
| JP-S63271411-A | CONTACT LENS MATERIAL | TOME SANGYO KK | 1988-11-09 | — | — | JP | disclosed |