Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353539 | 0.79 | MTNR1A (0.42) | KDM4ECA4MTNR1AMTNR1BLMNA | |
| SCHEMBL10339694 | 0.79 | KDM4E (0.39) | POLBKDM4ECA4MTNR1AMTNR1B | |
| SCHEMBL43675 | 0.79 | MTNR1A (0.42) | KDM4ECA4MTNR1AMTNR1BLMNA | |
| SCHEMBL8743586 | 0.79 | KDM4E (0.39) | POLBKDM4ECA4MTNR1AMTNR1B | |
| SCHEMBL4306370 | 0.79 | KDM4E (0.39) | POLBKDM4ECA4MTNR1AMTNR1B | |
| SCHEMBL542873 | 0.74 | KDM4E (0.50) | POLBKDM4ECA4MTNR1AMTNR1B | |
| SCHEMBL1453272 | 0.74 | CA4 (0.48) | POLBKDM4ECA4MTNR1AMTNR1B | |
| SCHEMBL12394 | 0.74 | KMT2A (0.54) | POLBKDM4ECA4MTNR1AMTNR1B | |
| SCHEMBL10835046 | 0.73 | LTA4H (0.47) | MAOALTA4HTSHRALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL8909178 | 0.72 | KMT2A (0.52) | POLBKDM4ECA4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |