Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL8733622

Cc1c(C)c(C)c(-c2ccccc2I)c(C)c1C.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.33

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.33
ELANE P08246 1/20 0.33
MAOA P21397 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
PGAM1 P18669 1/20 0.30
PTPN1 P18031 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL8735167 0.81 TRPA1 (0.39) GPR3MEN1KMT2APTPN1PDK2
Trifluoromethanesulfonic Acid SCHEMBL8737223 0.79 POLB (0.40) GPR3MEN1MAPTKMT2APTPN1
Trifluoromethanesulfonic Acid SCHEMBL4660340 0.78 PTPN1 (0.42) GPR3PTPN1
Trifluoromethanesulfonic Acid SCHEMBL30131111 0.78 PTPN1 (0.42) GPR3PTPN1
Trifluoromethanesulfonic Acid SCHEMBL2902965 0.77 MAPT (0.35) GPR3MAOAMEN1MAPTKMT2A
Trifluoromethanesulfonic Acid SCHEMBL8736614 0.76 ALDH1A1 (0.39) GPR3MEN1KMT2APTPN1
Trifluoromethanesulfonic Acid SCHEMBL8736573 0.76 PTPN5 (0.43) GPR3MAPTPTPN1PDK2
Trifluoromethanesulfonic Acid SCHEMBL8735155 0.75 PTPN1 (0.37) GPR3PTPN1
Trifluoromethanesulfonic Acid SCHEMBL5851785 0.75 SLC22A12 (0.46) MEN1MAPTKMT2APTPN1PDK2
Trifluoromethanesulfonic Acid SCHEMBL27556244 0.75 TRPA1 (0.45) MAPTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP disclosed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US disclosed