Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL8735155

Ic1ccc(-c2ccccc2I)cc1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.37
GPR3 P46089 1/20 0.34
PTGS2 P35354 4/20 0.33
PTGS1 P23219 2/20 0.33
F10 P00742 1/20 0.33
GRIA4 P48058 1/20 0.33
HSD11B1 P28845 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
PTPN5 P54829 1/20 0.31
KCNH2 Q12809 1/20 0.31
ADAMTS4 O75173 1/20 0.31
TDP2 O95551 1/20 0.31
NSD2 O96028 1/20 0.31
PLA2G1B P04054 1/20 0.31
HSP90AA1 P07900 1/20 0.31
CCR6 P51684 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL4660340 0.90 PTPN1 (0.42) PTPN1GPR3PTGS2PTPN5CASP1
Trifluoromethanesulfonic Acid SCHEMBL30131111 0.90 PTPN1 (0.42) PTPN1GPR3PTGS2PTPN5CASP1
Trifluoromethanesulfonic Acid SCHEMBL1805194 0.89 PTGS2 (0.46) PTPN1PTGS2PTGS1GRIA4HSD11B1
Trifluoromethanesulfonic Acid SCHEMBL8735178 0.87 PTGS2 (0.45) PTPN1PTGS2PTGS1HSP90AA1ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL8737223 0.87 POLB (0.40) PTPN1GPR3PTGS2PTGS1GRIA4
Trifluoromethanesulfonic Acid SCHEMBL1270052 0.84 HSD11B1 (0.40) PTPN1HSD11B1PLA2G1BATG4BCA1
Trifluoromethanesulfonic Acid SCHEMBL387254 0.83 HDAC4 (0.47) PTPN1PTGS2HSP90AA1MMP2MMP9
Trifluoromethanesulfonic Acid SCHEMBL27707915 0.82 PTPN1 (0.53) PTPN1PTPN5CA1CA2MMP1
Trifluoromethanesulfonic Acid SCHEMBL3987054 0.82 PTGS2 (0.40) PTGS2HSD11B1CA1CA2ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL1140970 0.81 PPARG (0.39) PTPN1PTGS2HSD11B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP disclosed