Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | C1R | P00736 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL27556244 | 0.85 | TRPA1 (0.45) | TRPA1ATMHTTNPC1LMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL8733622 | 0.81 | GPR3 (0.33) | PDK2PTPN1GPR3MEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL28564485 | 0.78 | TRPA1 (0.52) | TRPA1ATMPDK2HTTNPC1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8737223 | 0.77 | POLB (0.40) | PDK2KCNH2NPC1LMNATP53 | |
| Trifluoromethanesulfonic Acid SCHEMBL8736614 | 0.77 | ALDH1A1 (0.39) | NPC1TSHRRAB9AHSD11B1PTPN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8736573 | 0.77 | PTPN5 (0.43) | PDK2KCNH2NPC1RAB9ASDHB | |
| O-Xylene SCHEMBL2990079 | 0.76 | ACHE (0.48) | TRPA1ATMPDK2NPC1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL5851785 | 0.76 | SLC22A12 (0.46) | PDK2HTTLMNATP53TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL4660340 | 0.76 | PTPN1 (0.42) | HTTLMNAHSD17B10CASP1PTPN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL30131111 | 0.76 | PTPN1 (0.42) | HTTLMNAHSD17B10CASP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697387-B1 | Improved method for the preparation of iodonium salts | DOW CORNING (US) | 1998-04-22 | — | — | EP | disclosed |
| US-5426222-A | Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent | DOW CORNING CORPORATION (US) | 1995-06-20 | — | — | US | disclosed |