Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTL | Q8NG68 | 11/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 2/20 | 0.30 |
| ▸ | CDC25B | P30305 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733662 | 1.00 | TTL (0.51) | TTLPOLBMAPTBCHEACHE | |
| SCHEMBL8733660 | 0.86 | TTL (0.39) | TTLPOLBMAPT | |
| Andalusol SCHEMBL3669300 | 0.80 | TTL (0.52) | TTLMAPTBCHEACHEHSD11B1 | |
| SCHEMBL8733677 | 0.78 | MAPT (0.44) | TTLPOLBMAPTBCHEACHE | |
| SCHEMBL8733674 | 0.78 | MAPT (0.44) | TTLPOLBMAPTBCHEACHE | |
| SCHEMBL8731622 | 0.69 | MAPT (0.40) | POLBMAPT | |
| SCHEMBL29551597 | 0.69 | MAPT (0.40) | POLBMAPT | |
| SCHEMBL29922526 | 0.69 | MAPT (0.40) | POLBMAPT | |
| SCHEMBL8731628 | 0.69 | ALDH1A1 (0.57) | POLBMAPT | |
| SCHEMBL15220009 | 0.69 | ALDH1A1 (0.57) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773005-A | ENZYME INHIBITORS, ANTISECRETORY AGENTS AND ANTIANDROGENS | KABUSHIKI KAISHA YAKURIGAKU CHUO KENKYUSHO (JP) | 1998-06-30 | — | — | US | claimed |
| US-5773005-A | ENZYME INHIBITORS, ANTISECRETORY AGENTS AND ANTIANDROGENS | KABUSHIKI KAISHA YAKURIGAKU CHUO KENKYUSHO (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0747048-A2 | Diterpenes and flavonoids as 5-alpha-reductase inhibitors | Kabushiki Kaisha Yakurigaku Chuo Kenkyusho (JP) | 1996-12-11 | — | — | EP | disclosed |