Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 13/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733753 | 1.00 | TBXA2R (0.57) | TBXA2RGAAHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL8731670 | 0.82 | TBXA2R (0.82) | TBXA2R | |
| SCHEMBL8728396 | 0.81 | TBXA2R (0.63) | TBXA2RALDH1A1 | |
| SCHEMBL8734677 | 0.76 | TBXA2R (0.84) | TBXA2RALDH1A1 | |
| SCHEMBL8734706 | 0.75 | TBXA2R (0.82) | TBXA2RALDH1A1 | |
| SCHEMBL8734662 | 0.74 | TBXA2R (0.83) | TBXA2RALDH1A1MAPT | |
| SCHEMBL8733779 | 0.74 | TBXA2R (0.70) | TBXA2R | |
| SCHEMBL8730165 | 0.74 | TBXA2R (0.70) | TBXA2R | |
| SCHEMBL8734691 | 0.74 | TBXA2R (0.70) | TBXA2RALDH1A1MAPT | |
| SCHEMBL5673556 | 0.74 | TBXA2R (0.85) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |