Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076740 | 0.88 | HPGD (0.53) | SCN9AHPGD | |
| SCHEMBL6035722 | 0.86 | BCHE (0.63) | — | |
| SCHEMBL8875136 | 0.81 | PTGES (0.58) | SCN9APTGESALOX5PPARG | |
| SCHEMBL8875155 | 0.81 | PTGES (0.58) | SCN9APTGESALOX5PPARG | |
| SCHEMBL8875142 | 0.81 | PTGES (0.58) | SCN9APTGESALOX5PPARG | |
| SCHEMBL991380 | 0.81 | KMT2A (0.54) | HPGD | |
| SCHEMBL29639215 | 0.81 | KMT2A (0.54) | HPGD | |
| SCHEMBL9078345 | 0.81 | CXCL8 (0.49) | PTGESALOX5PPARG | |
| SCHEMBL10191805 | 0.79 | SMN1; SMN2 (0.61) | ABCB1ABCG2 | |
| Hydrochloric Acid SCHEMBL2532791 | 0.79 | KMT2A (0.55) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641766-B1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |