Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 8/20 | 0.46 |
| ▸ | THRA | P10827 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077930 | 0.85 | MCHR1 (0.52) | MCHR1THRBTHRAMEN1KMT2A | |
| SCHEMBL8733926 | 0.80 | HTR2C (0.50) | MEN1KMT2AALOX5PPARG | |
| Oxalic Acid SCHEMBL9077421 | 0.78 | — | — | |
| SCHEMBL8420618 | 0.77 | HTR2C (0.50) | FFAR1MEN1KMT2A | |
| SCHEMBL9075917 | 0.76 | CHRM1 (0.45) | FFAR1MEN1KMT2AALOX5PPARG | |
| SCHEMBL16050401 | 0.74 | THRB (0.50) | MCHR1THRBTHRAMEN1KMT2A | |
| SCHEMBL9077423 | 0.74 | SIGMAR1 (0.42) | MCHR1ALOX5PPARG | |
| SCHEMBL9077270 | 0.73 | PTGDR2 (0.49) | FFAR1MEN1KMT2A | |
| SCHEMBL9078345 | 0.72 | CXCL8 (0.49) | FFAR1AKR1B1ALOX5PPARG | |
| SCHEMBL8734857 | 0.70 | FFAR1 (0.54) | THRBTHRAFFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |