SCHEMBL258575

SCHEMBL258575

ClCc1cc(CCl)c(CCl)c(CCl)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175914 0.83 L3MBTL1 (0.30) L3MBTL1
SCHEMBL8734181 0.81 HSPA5 (0.35)
SCHEMBL5885566 0.77 MCL1 (0.32)
SCHEMBL28996833 0.74 KDM4E (0.38)
SCHEMBL1050358 0.73 CA1 (0.33) TSHR
SCHEMBL11697988 0.71 PTGS2 (0.41) TSHR
SCHEMBL509442 0.70 HSPA5 (0.35)
SCHEMBL29208987 0.69 MAPT (0.42)
SCHEMBL1264631 0.69
SCHEMBL29587349 0.69 CA1 (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2514788-B1 Phosphorus-sulfur flame retardant additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-01 EP disclosed
EP-2514788-A1 Phosphorus-sulfur flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-10-24 EP disclosed
US-8058332-B2 Phosphorus-sulfur FR additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-15 US disclosed
US-20110034573-A1 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME THE DOW CHEMICAL COMPANY 2011-02-10 US disclosed
EP-2125946-A2 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME Dow Global Technologies Inc. (US) 2009-12-02 EP disclosed
WO-2008088487-A2 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES, INC. (US) 2008-07-24 WO disclosed
US-20080153950-A1 Phosphorus-sulfur FR additives and polymer systems containing same DCOMCO, INC. 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153950-A1 Phosphorus-sulfur FR additives and polymer systems containing same TST, FRG1, PFAS L3MBTL1 1891/4885TSHR 1687/4885
US-20110034573-A1 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME TST, FRG1, PFAS L3MBTL1 1891/4885TSHR 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.