Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731672 | 0.88 | TBXA2R (0.61) | TBXA2RGBA1POLBPKMNPY5R | |
| SCHEMBL8734189 | 0.82 | TBXA2R (0.64) | TBXA2RGBA1 | |
| SCHEMBL8734707 | 0.82 | TBXA2R (0.64) | TBXA2RPOLBMAPTNPY5RALDH1A1 | |
| SCHEMBL8734679 | 0.80 | TBXA2R (0.67) | TBXA2RPOLBNPY5RNPY1RALDH1A1 | |
| SCHEMBL8734692 | 0.78 | KMT2A (0.52) | TBXA2RMAPTALDH1A1 | |
| SCHEMBL8728399 | 0.77 | TBXA2R (0.48) | TBXA2RMAPTPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL8728445 | 0.76 | TBXA2R (0.57) | TBXA2RGBA1NPY5RNPY1RALDH1A1 | |
| Water SCHEMBL2762310 | 0.76 | TBXA2R (0.63) | TBXA2RPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL8734665 | 0.75 | TBXA2R (0.66) | TBXA2RMAPTNPY5RNPY1RALDH1A1 | |
| SCHEMBL8730030 | 0.73 | TBXA2R (0.61) | TBXA2RGBA1NPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |