Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | APOB | P04114 | 1/20 | 0.50 |
| ▸ | MTTP | P55157 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731672 | 0.84 | TBXA2R (0.61) | TBXA2RALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL8734192 | 0.82 | TBXA2R (0.49) | TBXA2RALDH1A1MAPTPOLBNPY5R | |
| SCHEMBL8734692 | 0.81 | KMT2A (0.52) | TBXA2RALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8734679 | 0.80 | TBXA2R (0.67) | TBXA2RALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL8734706 | 0.79 | TBXA2R (0.82) | TBXA2RALDH1A1TP53APOBMTTP | |
| Water SCHEMBL2762310 | 0.78 | TBXA2R (0.63) | TBXA2RALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8734665 | 0.78 | TBXA2R (0.66) | TBXA2RALDH1A1MAPTHPGDNPY5R | |
| SCHEMBL8728399 | 0.78 | TBXA2R (0.48) | TBXA2RALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8733559 | 0.74 | TBXA2R (0.54) | TBXA2RLMNASMN1; SMN2 | |
| SCHEMBL8728445 | 0.72 | TBXA2R (0.57) | TBXA2RALDH1A1MEN1KMT2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |