Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731672 | 0.89 | TBXA2R (0.61) | KMT2AMEN1ALDH1A1TBXA2RKDM4E | |
| Water SCHEMBL2762310 | 0.88 | TBXA2R (0.63) | KMT2AMEN1ALDH1A1TBXA2R | |
| SCHEMBL8734679 | 0.85 | TBXA2R (0.67) | KMT2AMEN1ALDH1A1TBXA2RLMNA | |
| SCHEMBL8733559 | 0.83 | TBXA2R (0.54) | TBXA2RLMNA | |
| SCHEMBL8734707 | 0.81 | TBXA2R (0.64) | KMT2AMEN1ALDH1A1TBXA2RMAPT | |
| SCHEMBL8734691 | 0.79 | TBXA2R (0.70) | KMT2AMEN1ALDH1A1CYP2C9TBXA2R | |
| SCHEMBL8734665 | 0.78 | TBXA2R (0.66) | ALDH1A1TBXA2RMAPT | |
| SCHEMBL8734192 | 0.78 | TBXA2R (0.49) | ALDH1A1TBXA2RMAPT | |
| SCHEMBL8728399 | 0.78 | TBXA2R (0.48) | ALDH1A1TBXA2RKDM4EGAAMAPT | |
| SCHEMBL8728445 | 0.76 | TBXA2R (0.57) | KMT2AMEN1ALDH1A1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |