Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.67 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | ACACB | O00763 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731672 | 0.89 | TBXA2R (0.61) | TBXA2RNPY5RNPY1RPOLBALDH1A1 | |
| SCHEMBL8734692 | 0.85 | KMT2A (0.52) | TBXA2RALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8734665 | 0.84 | TBXA2R (0.66) | TBXA2RNPY5RNPY1RALDH1A1 | |
| Water SCHEMBL2762310 | 0.83 | TBXA2R (0.63) | TBXA2RALDH1A1MEN1KMT2A | |
| SCHEMBL8734707 | 0.80 | TBXA2R (0.64) | TBXA2RNPY5RPOLBALDH1A1LMNA | |
| SCHEMBL8734677 | 0.80 | TBXA2R (0.84) | TBXA2RNPY5RNPY1RACACBHDAC3 | |
| SCHEMBL8728399 | 0.80 | TBXA2R (0.48) | TBXA2RALDH1A1 | |
| SCHEMBL8734192 | 0.80 | TBXA2R (0.49) | TBXA2RNPY5RNPY1RACACBPOLB | |
| SCHEMBL8733559 | 0.79 | TBXA2R (0.54) | TBXA2RLMNA | |
| SCHEMBL8733718 | 0.77 | TBXA2R (0.71) | TBXA2RNPY5RNPY1RACACBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |