Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29847401 | 1.00 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL873159 | 0.83 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL741042 | 0.79 | SLC22A12 (0.53) | SMN1; SMN2ALDH1A1CCR1CCR5CCR8 | |
| SCHEMBL827782 | 0.79 | NR4A2 (0.61) | SMN1; SMN2ALDH1A1PARP1CCR1CCR5 | |
| SCHEMBL5539375 | 0.79 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL16289832 | 0.79 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL4758609 | 0.79 | LMNA (0.56) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL4644505 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1PARP1CCR1CCR5 | |
| SCHEMBL22277957 | 0.79 | SMN1; SMN2 (0.51) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL18544878 | 0.79 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113176253-B | Occult blood indicator for animal excrement and application thereof | 上海麦可信生物科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-110437143-B | Benzyl substituted quinoline and derivative and synthesis method thereof | 湘潭大学 | 2022-08-09 | — | — | CN | claimed |
| CN-113176253-A | Animal excrement occult blood indicator and application thereof | 上海麦可信生物科技有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-109776406-B | Method for cross coupling of ether compound and quinoline derivative | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-110272383-A | 2- is alkylated 4- methylquinoline, derivative and its synthetic method | 湘潭大学 | 2019-09-24 | — | — | CN | claimed |
| US-9796800-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2017-10-24 | — | — | US | claimed |
| US-20160108153-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2016-04-21 | — | — | US | claimed |
| CN-103154044-B | Process for producing polydienes | BRIDGESTONE CO.,LTD. (JP) | 2016-02-17 | — | — | CN | claimed |
| US-9249244-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2016-02-02 | — | — | US | claimed |
| EP-2619233-A1 | PROCESS FOR PRODUCING POLYDIENES | Bridgestone Corporation (JP) | 2013-07-31 | — | — | EP | claimed |
| CN-103154044-A | Process for producing polydienes | BRIDGESTONE CORP | 2013-06-12 | — | — | CN | claimed |
| WO-2012040026-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | WO | claimed |
| US-7692016-B2 | Process for the synthesis of quinoline derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-04-06 | — | — | US | claimed |
| WO-2007060685-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF QUINOLINE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-05-31 | — | — | WO | claimed |
| US-20070123708-A1 | Process for the synthesis of quinoline derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-05-31 | — | — | US | claimed |
| EP-0039205-B1 | SELECTIVE PRODUCTION OF DIALKYLBENZENES | MOBIL OIL CORPORATION (US) | 1985-01-30 | — | — | EP | claimed |
| US-3986833-A | TEST COMPOSITION, DEVICE, AND METHOD FOR THE DETECTION OF PEROXIDATIVELY ACTIVE SUBSTANCES | MILES LABORATORIES, INC. (US) | 1976-10-19 | — | — | US | claimed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| US-4108668-A | Light-sensitive silver halide photographic materials | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |
| US-3986833-A | TEST COMPOSITION, DEVICE, AND METHOD FOR THE DETECTION OF PEROXIDATIVELY ACTIVE SUBSTANCES | MILES LABORATORIES, INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | KLK5, KLK1, KLKB1 | HTR1A 3824/4885ADRA1D 3274/4885ADRA1A 3776/4885 |
| US-20070123708-A1 | Process for the synthesis of quinoline derivatives | NDUFS4, NDUFS3, NDUFS5 | HTR1A 2093/4885ADRA1D 3048/4885ADRA1A 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.