SCHEMBL8734378

SCHEMBL8734378

Oc1ccc(C[CH]c2ccccc2O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.47
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
ALOX12 P18054 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 6/20 0.42
CA2 P00918 6/20 0.42
CA9 Q16790 5/20 0.40
CYP19A1 P11511 1/20 0.40
TRPA1 O75762 1/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
KDM1A O60341 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15941726 0.88 TRPA1 (0.47) TRIM24TRIM33KDM4EMEN1ALDH1A1
SCHEMBL1637018 0.79 ENPP2 (0.46) TRIM24TRIM33KDM4EALDH1A1MAPT
SCHEMBL5115664 0.79 KDM4E (0.43) KDM4EALDH1A1MAPTCA2CYP19A1
SCHEMBL28869157 0.78 GCGR (0.44) KDM4EMEN1KMT2A
SCHEMBL4348469 0.75 ESR1 (0.45) KEAP1MEN1MAPTKMT2ACA12
SCHEMBL6535023 0.72 GPR52 (0.44) TRIM24TRIM33KDM4EMEN1ALDH1A1
SCHEMBL28736735 0.72 KDM4E (0.63) KDM4EMEN1ALDH1A1MAPTTHRB
SCHEMBL5074495 0.72 TRIM24 (0.52) TRIM24TRIM33KDM4EMEN1ALDH1A1
SCHEMBL8668773 0.72 ABAT (0.50) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL1838566 0.72 TRIM24 (0.52) TRIM24TRIM33KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686274-B1 NOVEL MATRIX RESIN FOR HIGH-TEMPERATURE STABLE PHOTOIMAGEABLE COMPOSITIONS CLARIANT FINANCE BVI LTD (VG) 1998-12-23 EP claimed