Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735652 | 0.84 | HSD17B1 (0.49) | HSD17B1HSD17B2CYP11B1CYP11B2GSTP1 | |
| SCHEMBL11723042 | 0.80 | CYP2A6 (0.52) | HSD17B1HSD17B2CYP11B1CYP11B2GSTP1 | |
| SCHEMBL7937480 | 0.80 | CYP1A2 (0.46) | HSD17B1HSD17B2CYP11B1CYP11B2GSTP1 | |
| SCHEMBL9054823 | 0.78 | CYP1A2 (0.52) | HSD17B1HSD17B2CYP11B1CYP11B2GSTP1 | |
| SCHEMBL9057774 | 0.74 | CYP1A2 (0.47) | GSTP1KDM4ECYP1A2CYP2A6NPC1 | |
| SCHEMBL1912033 | 0.71 | DYRK1A (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15342387 | 0.71 | DYRK1A (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL82486 | 0.71 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8734461 | 0.70 | CYP1A2 (0.39) | HSD17B2CYP11B1CYP11B2GSTP1MAPT | |
| SCHEMBL8732840 | 0.70 | GAPDH (0.53) | CA12CA9MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826680-A1 | Dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods | ELI LILLY AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |