SCHEMBL8734627

SCHEMBL8734627

CCOP(=O)(COS(=O)(=O)c1c(C)cccc1Cl)OCC

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 3/20 0.32
LMNA P02545 3/20 0.32
NR3C1 P04150 1/20 0.32
ESR1 P03372 1/20 0.31
THRB P10828 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
RORC P51449 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 2/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732411 0.94 SLC40A1 (0.32) SLC40A1HSD17B10MEN1KMT2AALDH1A1
SCHEMBL8732012 0.92 HSD17B10 (0.35) HSD17B10MEN1KMT2AALDH1A1LMNA
SCHEMBL8731903 0.90 NR3C1 (0.33) SLC40A1HSD17B10MEN1KMT2ANR3C1
SCHEMBL8734903 0.88 SLC40A1 (0.33) SLC40A1HSD17B10MEN1KMT2AALDH1A1
SCHEMBL8763963 0.87 ESR1 (0.32) SLC40A1ALDH1A1LMNANR3C1ESR1
SCHEMBL8731899 0.87 SLC40A1 (0.32) SLC40A1HSD17B10MEN1KMT2AALDH1A1
SCHEMBL8763944 0.86 SLC40A1 (0.34) SLC40A1KMT2AALDH1A1LMNANR3C1
SCHEMBL8734825 0.83 ELANE (0.34) HSD17B10MEN1KMT2AALDH1A1LMNA
SCHEMBL27289740 0.83 PNMT (0.38) HSD17B10MEN1KMT2A
SCHEMBL8764015 0.83 SLC40A1 (0.36) SLC40A1KMT2AALDH1A1LMNANR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed