SCHEMBL8764015

SCHEMBL8764015

Cc1cccc(Cl)c1S(=O)(=O)OCP(=O)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.36
NR3C1 P04150 1/20 0.34
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
CCR1 P32246 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ESR1 P03372 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CCR4 P51679 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764723 0.89 SMN1; SMN2 (0.35) ALDH1A1LMNAKMT2ASMN1; SMN2CCR4
SCHEMBL8763806 0.87 SLC40A1 (0.36) SLC40A1NR3C1ALDH1A1LMNAALOX15
SCHEMBL8734975 0.87 SMN1; SMN2 (0.40) SLC40A1NR3C1ALDH1A1LMNAALOX15
SCHEMBL8763944 0.85 SLC40A1 (0.34) SLC40A1NR3C1ALDH1A1LMNAALOX15
SCHEMBL8764044 0.85 SMN1; SMN2 (0.36) SLC40A1NR3C1ALDH1A1LMNAALOX15
SCHEMBL8734627 0.83 SLC40A1 (0.33) SLC40A1NR3C1ALDH1A1LMNAALOX15
SCHEMBL8764539 0.83 ALDH1A1 (0.34) SLC40A1NR3C1ALDH1A1LMNAKMT2A
SCHEMBL8763947 0.83 ESR1 (0.33) SLC40A1NR3C1ALDH1A1LMNAALOX15
SCHEMBL8734903 0.82 SLC40A1 (0.33) SLC40A1NR3C1ALDH1A1LMNAHTT
SCHEMBL8732446 0.82 NR3C1 (0.35) SLC40A1NR3C1ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed