SCHEMBL8734725

SCHEMBL8734725

CCSc1ccccc1S(=O)(=O)OC[PH](=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.33
ALOX15 P16050 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
PTGS2 P35354 7/20 0.33
HPGD P15428 4/20 0.33
PKM P14618 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
NPSR1 Q6W5P4 2/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAP2K7 O14733 1/20 0.30
S100A4 P26447 1/20 0.30
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30
MITF O75030 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734580 0.85 ALDH1A1 (0.33) HSD17B10ALDH1A1MAPTHPGDTDP1
SCHEMBL8854638 0.83 ALOX15 (0.32) HSD17B10ALOX15ALDH1A1MAPTHPGD
SCHEMBL27466462 0.80 ALOX15 (0.31) HSD17B10ALOX15ALDH1A1MAPTHPGD
SCHEMBL8734593 0.80 GAA (0.32) MAPTHPGDNPSR1GAAL3MBTL1
SCHEMBL8732338 0.80 GABRA1 (0.31) HPGD
SCHEMBL8735591 0.79 FFAR4 (0.35) ALDH1A1HPGDPKML3MBTL1HTT
SCHEMBL8734839 0.79 LMNA (0.30) PKMLMNA
SCHEMBL8732625 0.79 KAT6A (0.32) HPGD
SCHEMBL8729821 0.77 HSD17B10 (0.36) HSD17B10ALOX15ALDH1A1MAPTHPGD
SCHEMBL27449558 0.76 ALOX15 (0.31) HSD17B10ALOX15ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed