SCHEMBL8734733

SCHEMBL8734733

CCc1cccc(F)c1S(=O)(=O)OCP(=O)(O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.35
KAT6A Q92794 5/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
PKM P14618 1/20 0.32
PKLR P30613 1/20 0.32
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
ALDH1A1 P00352 2/20 0.31
CXCL8 P10145 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PTPN5 P54829 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732694 0.83 CA12 (0.35) KEAP1KAT6APKMPKLRLMNA
SCHEMBL8734721 0.82 GABRA1 (0.38) GABRA1GABRB2LMNASMN1; SMN2ALDH1A1
SCHEMBL8731835 0.81 KAT6A (0.34) KAT6AALDH1A1MAPTHPGDALOX15
SCHEMBL8730144 0.81 KEAP1 (0.30) KEAP1
SCHEMBL8732707 0.81
SCHEMBL8734484 0.81 LMNA (0.32) GABRA1GABRB2LMNASMN1; SMN2ALDH1A1
SCHEMBL8734989 0.81 KDM4E (0.32) KAT6APKMPKLRLMNAHPGD
SCHEMBL8732676 0.80 CA12 (0.31)
SCHEMBL8735535 0.80 F2R (0.34) GABRA1GABRB2ALDH1A1PTPN5GAA
SCHEMBL8734910 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed