SCHEMBL8734769

SCHEMBL8734769

CCP(=O)(COS(=O)(=O)c1c(F)cccc1C(F)(F)F)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.33
CTSS P25774 3/20 0.32
PTGES2 Q9H7Z7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9069741 0.89 ALDH1A1 (0.32)
SCHEMBL8735717 0.88 SLC6A2 (0.31) CTSS
SCHEMBL8730162 0.88 CTSS (0.32) CTSS
SCHEMBL8734806 0.88 TRPM8 (0.32) TRPM8PTGES2
SCHEMBL8732451 0.87 TRPM8 (0.32) TRPM8PTGES2
SCHEMBL8729954 0.86 CTSS (0.34) CTSS
SCHEMBL8732856 0.85 LMNA (0.30) TRPM8
SCHEMBL8734756 0.85 KCNK3 (0.40)
SCHEMBL8735030 0.85 CTSS (0.31) TRPM8CTSS
SCHEMBL8735711 0.85 TRPM8 (0.31) TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US claimed