Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310351 | 0.87 | HSD17B10 (0.53) | KMT2AMEN1GPR174HSD17B10MAPT | |
| SCHEMBL8735211 | 0.81 | HSD17B10 (0.45) | KMT2AMEN1HSD17B10EPHX2 | |
| SCHEMBL17284155 | 0.76 | MEN1 (0.45) | L3MBTL1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL28804381 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL305727 | 0.71 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL11028218 | 0.70 | HTT (0.77) | ALDH1A1POLBHTTKMT2AMEN1 | |
| SCHEMBL26082853 | 0.69 | MEN1 (0.62) | ALDH1A1POLBHTTKMT2AMEN1 | |
| SCHEMBL8203974 | 0.69 | LMNA (0.53) | L3MBTL1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL21073953 | 0.68 | NAALAD2 (0.53) | L3MBTL1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL28964245 | 0.68 | TSHR (0.46) | ALDH1A1HTTKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | claimed |
| WO-1995005408-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1995-02-23 | — | — | WO | claimed |
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | disclosed |
| EP-0714417-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005408-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1995-02-23 | — | — | WO | disclosed |