Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310351 | 0.85 | HSD17B10 (0.53) | HSD17B10CNR1MEN1KMT2ANPY5R | |
| SCHEMBL8735219 | 0.81 | L3MBTL1 (0.44) | HSD17B10MEN1KMT2AEPHX2 | |
| SCHEMBL17284155 | 0.74 | MEN1 (0.45) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL28804381 | 0.72 | ALDH1A1 (0.50) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL8735991 | 0.72 | CNR1 (0.43) | HSD17B10CNR1CA12CA1CA2 | |
| SCHEMBL305727 | 0.69 | ALDH1A1 (0.45) | HSD17B10CA12CA9MEN1KMT2A | |
| SCHEMBL1326464 | 0.69 | NLRP3 (0.39) | KMT2A | |
| SCHEMBL28964245 | 0.67 | TSHR (0.46) | MEN1KMT2AEPHX2 | |
| SCHEMBL2951343 | 0.66 | NAPRT (0.44) | HSD17B10MEN1KMT2AKLK7 | |
| SCHEMBL7242603 | 0.66 | HSD17B10 (0.66) | HSD17B10CNR1MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | claimed |
| WO-1995005408-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1995-02-23 | — | — | WO | claimed |
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | disclosed |
| EP-0714417-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005408-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1995-02-23 | — | — | WO | disclosed |