Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736550 | 0.72 | HTR2A (0.32) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL6058559 | 0.68 | KDM1A (0.41) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL8736494 | 0.67 | KDM1A (0.33) | KDM1A | |
| SCHEMBL8736634 | 0.63 | KDM1A (0.36) | KDM1A | |
| SCHEMBL5608796 | 0.60 | KDM1A (0.33) | KDM1A | |
| SCHEMBL8733740 | 0.60 | LMNA (0.34) | KDM1A | |
| SCHEMBL8737332 | 0.59 | KDM1A (0.33) | KDM1A | |
| SCHEMBL7398947 | 0.57 | KDM1A (0.39) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL4658876 | 0.56 | HTR2A (0.35) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL9489237 | 0.55 | KDM1A (0.44) | KDM1AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877607-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1998-11-18 | — | — | EP | claimed |
| WO-1997027846-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1997-08-07 | — | — | WO | claimed |