Phthalic Acid

Phthalic Acid

SCHEMBL9869587

Cc1ccc(N)c(N)c1C.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
ALOX15 P16050 1/20 0.50
MYC P01106 3/20 0.47
KMT2A Q03164 3/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP1A2 P05177 2/20 0.46
AKR1C3 P42330 2/20 0.46
MEN1 O00255 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
AKR1B10 O60218 1/20 0.46
TRPA1 O75762 1/20 0.46
ABCB11 O95342 1/20 0.46
DHFR P00374 1/20 0.46
LMNA P02545 1/20 0.46
MPO P05164 1/20 0.46
CHRM1 P11229 1/20 0.46
AKR1B1 P15121 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL21957804 0.87 ALDH1A1 (0.52) ALDH1A1ALOX15MYCKMT2ACYP3A4
Carbamic Acid SCHEMBL8735463 0.83 TDP1 (0.41) ALDH1A1KMT2ACYP3A4MEN1TDP1
SCHEMBL3619161 0.79 MYC (0.53) ALDH1A1ALOX15MYCKMT2ACYP3A4
SCHEMBL1149742 0.79 KDM4E (0.48) ALDH1A1MYCKMT2ACYP3A4CYP2C9
SCHEMBL555823 0.79 KDM4E (0.48) ALDH1A1ALOX15KMT2ACYP3A4CYP1A2
Salicylic Acid SCHEMBL21957704 0.78 ALDH1A1 (0.58) ALDH1A1ALOX15MYCKMT2ACYP3A4
SCHEMBL29366969 0.78 POLB (0.48) ALDH1A1ALOX15CYP3A4CYP1A2TDP1
SCHEMBL34364 0.78 POLB (0.48) ALDH1A1ALOX15CYP3A4CYP1A2TDP1
Hydrochloric Acid SCHEMBL27932861 0.77 KMT2A (0.48) ALDH1A1ALOX15KMT2ACYP3A4CYP1A2
SCHEMBL10800974 0.77 KDM4E (0.47) ALDH1A1MYCKMT2ACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5023303-A Coatings, steel plates DSM RESINS B.V., ZWOLLE, THE NETHERLANDS 1991-06-11 US disclosed