SCHEMBL873555

SCHEMBL873555

CC(=O)NOc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.48
MTNR1B P49286 5/20 0.48
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 1/20 0.47
NAPRT Q6XQN6 1/20 0.46
HSD17B10 Q99714 1/20 0.46
METAP2 P50579 7/20 0.44
METAP1 P53582 6/20 0.44
TSHR P16473 2/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX5 P09917 1/20 0.43
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylamine SCHEMBL27536507 0.92 MTNR1A (0.47) MTNR1AMTNR1BALDH1A1L3MBTL1MAPT
SCHEMBL27566696 0.92 PARP10 (0.53) MTNR1AMTNR1BMAPTTSHREPHX1
SCHEMBL27468317 0.92 METAP2 (0.50) MTNR1AMTNR1BALDH1A1L3MBTL1MAPT
Phenol SCHEMBL28099048 0.92 MTNR1A (0.43) MTNR1AMTNR1BALDH1A1L3MBTL1MAPT
SCHEMBL10506141 0.88 KMT2A (0.45) MTNR1AMTNR1BALDH1A1MAPTHSD17B10
SCHEMBL26805580 0.83 METAP2 (0.42) MTNR1AMTNR1BALDH1A1L3MBTL1MAPT
SCHEMBL3590919 0.81 METAP2 (0.46) METAP2METAP1TSHR
SCHEMBL3069934 0.80 SMN1; SMN2 (0.52) ALDH1A1MAPTMETAP2METAP1TSHR
SCHEMBL29852923 0.80 MEN1 (0.48) ALDH1A1MAPTTSHRCYP3A4
SCHEMBL4057878 0.80 TDP1 (0.46) ALDH1A1MAPTTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115124542-A Synthetic method of hydroxyphenyl-substituted pyrazolone indazole [ spiro ] pyrazolone compound 河南师范大学 2022-09-30 CN claimed
CN-115028645-A Synthesis method of bisindolone [ spiro ] benzodihydrofuran compound 河南师范大学 2022-09-09 CN claimed
CN-110372651-A A kind of synthetic method of the indene derivative of the skeleton containing benzofuran 上海师范大学 2019-10-25 CN claimed
CN-110033745-A A kind of guitar backplate and its processing method 吴东山 2019-07-19 CN claimed
CN-109734618-A A kind of preparation method and phenoxy acetamide class compound of phenoxy acetamide class compound 宜春学院 2019-05-10 CN claimed
CN-103694197-B Phenoxyacetamide compound and preparation method and application thereof UNIV HUAZHONG NORMAL 2015-07-15 CN claimed
CN-103694197-A Phenoxyacetamide compound and preparation method and application thereof UNIV HUAZHONG NORMAL 2014-04-02 CN claimed
EP-2643000-A2 THERAPEUTIC PIPERAZINES Dart Neuroscience (Cayman) Ltd (KY) 2013-10-02 EP claimed
WO-2012040258-A2 THERAPEUTIC PIPERAZINES HELICON THERAPEUTICS, INC. (US) 2012-03-29 WO claimed
US-20110065691-A1 THERAPEUTIC PIPERAZINES DART NEUROSCIENCE (CAYMAN) LTD. (KY) 2011-03-17 US claimed
EP-1299377-A2 SPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 2003-04-09 EP claimed
WO-2002000641-A2 SPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 2002-01-03 WO claimed
US-5475139-A Molecular rearrangement, aminolysis of n-phenylphenoxy acetamide and metallic phenol salt YUNG SHIN PHARM. IND. CO., LTD. (TW) 1995-12-12 US claimed
EP-4370508-B1 TRIAZOLE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2025-09-10 EP disclosed
US-20250214984-A1 COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2025-07-03 US disclosed
EP-4146645-B1 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF ONO PHARMACEUTICAL CO (JP) 2025-06-25 EP disclosed
EP-0128029-A2 Cephalosporin ester derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1984-12-12 EP disclosed
EP-0128027-A2 Cephalosporin esters, their production and use Takeda Chemical Industries, Ltd. (JP) 1984-12-12 EP disclosed
EP-0051261-A1 Process for the production of discharge-resist prints on textile materials CASSELLA Aktiengesellschaft (DE) 1982-05-12 EP disclosed
US-4291060-A Compounds derived from formylphenoxyacetic acid as antiviral agents in animals PFIZER INC. (US) 1981-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214984-A1 COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF KDM5A, KDM5B, KDM5D MTNR1A 2547/4885MTNR1B 3092/4885ALDH1A1 2221/4885
US-20110065691-A1 THERAPEUTIC PIPERAZINES PDE4A, PDE4B, PDE4D MTNR1A 624/4885MTNR1B 641/4885ALDH1A1 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.