Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 8/20 | 0.46 |
| ▸ | METAP1 | P53582 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650509 | 0.91 | PARP10 (0.57) | PARP10TSHRCA1CA2CA9 | |
| SCHEMBL3646258 | 0.83 | MEN1 (0.52) | METAP2METAP1MEN1KMT2APARP10 | |
| SCHEMBL10728474 | 0.83 | METAP2 (0.45) | METAP2METAP1MEN1KMT2APARP10 | |
| SCHEMBL31050921 | 0.81 | METAP2 (0.44) | METAP2METAP1MEN1KMT2APARP10 | |
| SCHEMBL10630086 | 0.81 | LMNA (0.50) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL873554 | 0.81 | PARP10 (0.45) | METAP2METAP1MEN1KMT2APARP10 | |
| SCHEMBL873555 | 0.81 | MTNR1A (0.48) | METAP2METAP1TSHR | |
| SCHEMBL6508655 | 0.81 | METAP2 (0.44) | METAP2METAP1MEN1KMT2APARP10 | |
| SCHEMBL17289473 | 0.81 | PARP10 (0.45) | MEN1KMT2APARP10TSHR | |
| SCHEMBL4632993 | 0.81 | CDK5 (0.44) | METAP2METAP1MEN1KMT2APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | claimed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | claimed |
| EP-0183174-B1 | SUBSTITUTED PHENOXY UREA, PROCESSES FOR ITS PREPARATION AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-10-26 | — | — | EP | claimed |
| EP-0183174-A2 | Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-06-04 | — | — | EP | claimed |
| EP-0014880-B1 | PHENOXYCARBOXYLIC ACID AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-09-22 | — | — | EP | claimed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | claimed |
| CN-117327061-A | Preparation method of tivalzanib hydrochloride and related substances | 武汉迈德森医药科技股份有限公司 | 2024-01-02 | — | — | CN | disclosed |
| EP-3438118-B1 | PEPTIDE DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES (JP) | 2023-03-29 | — | — | EP | disclosed |
| CN-111825611-B | 4(1H) -quinovone derivatives and uses thereof | 刘扶东 | 2022-09-09 | — | — | CN | disclosed |
| CN-108779146-B | Peptide derivatives and uses thereof | 东丽株式会社 | 2022-03-18 | — | — | CN | disclosed |
| CN-109971471-B | Fluorescent carbon dot for detecting phenoxy group-containing carbamate pesticide and application thereof | 中科(大连)快检科技有限公司 | 2022-01-14 | — | — | CN | disclosed |
| US-10792365-B2 | Peptide derivative and use thereof | TORAY INDUSTRIES, INC. (JP) | 2020-10-06 | — | — | US | disclosed |
| US-20190038757-A1 | PEPTIDE DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2019-02-07 | — | — | US | disclosed |
| EP-0029171-A1 | Azolyloxy-carboxylic acid N-oxy-amides, process and intermediates for their preparation, their use, herbicides containing them and their preparation | BAYER AG (DE) | 1981-05-27 | — | — | EP | disclosed |
| EP-0029183-A1 | Tetrazolyloxycarbon amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1981-05-27 | — | — | EP | disclosed |
| EP-0018497-A1 | Azolyloxy-acetamides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| US-3873600-A | Phenoxycarbamates | BRANDSTROM ARNE ELOF | 1975-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10792365-B2 | Peptide derivative and use thereof | NGLY1, NPPA, NPR1 | METAP2 611/4885METAP1 159/4885MEN1 229/4885 |
| US-20190038757-A1 | PEPTIDE DERIVATIVE AND USE THEREOF | NGLY1, NPPA, NPR1 | METAP2 611/4885METAP1 159/4885MEN1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.