Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247675 | 0.96 | ADRA1A (0.49) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL3668028 | 0.83 | ADRA2A (0.54) | ADRA1AIDO1ADRA2ACYP2D6ADRA1D | |
| SCHEMBL29390302 | 0.77 | SIGMAR1 (0.62) | ADRA1ASIGMAR1CYP11B2CYP2D6MEN1 | |
| SCHEMBL503849 | 0.77 | SIGMAR1 (0.62) | ADRA1ASIGMAR1CYP11B2CYP2D6MEN1 | |
| Ammonia Solution, Strong SCHEMBL8210515 | 0.75 | SIGMAR1 (0.60) | ADRA1ASIGMAR1CYP11B2CYP2D6MEN1 | |
| SCHEMBL30606845 | 0.75 | SIGMAR1 (0.60) | ADRA1ASIGMAR1CYP11B2CYP2D6MEN1 | |
| SCHEMBL8849605 | 0.73 | DDB1 (0.53) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL2984209 | 0.73 | IDO1 (0.48) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL5710152 | 0.73 | PIN1 (0.51) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL133896 | 0.73 | HTR2A (0.49) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103140476-A | Novel trpv3 modulators | ABBOTT LAB | 2013-06-05 | — | — | CN | claimed |
| CN-103140476-A | Novel trpv3 modulators | ABBOTT LAB | 2013-06-05 | — | — | CN | disclosed |