SCHEMBL9911203

SCHEMBL9911203

CP(=O)(N=[N+]=[N-])Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 3/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ANPEP P15144 1/20 0.38
LAP3 P28838 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
HCRTR1 O43613 1/20 0.37
PKM P14618 2/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25883278 1.00 SRC (0.48) SRCL3MBTL1TDP1HPGDKDM4E
SCHEMBL27836558 0.81 SRC (0.52) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL80417 0.81 SRC (0.52) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL2303782 0.81 SRC (0.52) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL873578 0.79 SRC (0.55) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL17305220 0.76 L3MBTL1 (0.50) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL27881894 0.76 SRC (0.47) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL2497223 0.76 L3MBTL1 (0.50) SRCL3MBTL1TDP1KDM4EALDH1A1
Phosphoric Acid SCHEMBL29974621 0.75 SRC (0.46) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL17860514 0.75 SRC (0.46) SRCL3MBTL1TDP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230264164-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY TRILINK BIOTECHNOLOGIES, LLC 2023-08-24 US disclosed
US-20230241257-A1 BIOTIN-MODIFIED DIMER AND USE THEREOF THE UNIVERSITY OF TOKYO (JP) 2023-08-03 US disclosed
US-10035774-B2 Pyrazolyl carboxylic acid and pyrazolyl urea derivative compounds MERCK SHARP & DOHME CORP. (US) 2018-07-31 US disclosed
US-20180193478-A1 ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI INC. 2018-07-12 US disclosed
US-20170362183-A1 PYRAZOLYL CARBOXYLIC ACID AND PYRAZOLYL UREA DERIVATIVE COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2017-12-21 US disclosed
US-9821493-B2 Microwave dipolar heating of energetic polymers for carbon fiber-matrix separation EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-11-21 US disclosed
US-20170252458-A1 ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE MORPHOTEK, INC. 2017-09-07 US disclosed
US-9617256-B2 Antibacterial agents ACHAOGEN, INC. (US) 2017-04-11 US disclosed
US-20160279834-A1 MICROWAVE DIPOLAR HEATING OF ENERGETIC POLYMERS FOR CARBON FIBER-MATRIX SEPARATION CRESTLINE DIRECT FINANCE, L.P. 2016-09-29 US disclosed
US-20160222423-A1 ENZYME-CATALYZED ENANTIOSELECTIVE AZIRIDINATION OF OLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-08-04 US disclosed
US-8524814-B2 Phosphonate bonding compositions HENKEL IRELAND LIMITED (DE) 2013-09-03 US disclosed
US-20130172341-A1 FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS MERCK SHARP & DOHME LLC 2013-07-04 US disclosed
US-8362022-B2 Selective subtype alpha 2 adrenergic agents and methods for use thereof ALLERGAN, INC. (US) 2013-01-29 US disclosed
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-08-09 US disclosed
US-20120142617-A1 ANTIVIRAL THERAPEUTIC AGENTS BIOCRYST PHARMACEUTICALS, INC. (US) 2012-06-07 US disclosed
US-20120022022-A1 NOVEL INHIBITORS OF CHYMASE HAWKINS MICHAEL J (US) 2012-01-26 US disclosed
US-20110165183-A1 PIPERIDINE DERIVATIVES AS JAK3 INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 2011-07-07 US disclosed
US-20110105526-A1 SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF ALLERGAN, INC. 2011-05-05 US disclosed
US-20110034517-A1 SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF ALLERGAN, INC. (US) 2011-02-10 US disclosed
US-20070249620-A1 Urea Derivative SANKYO COMPANY, LIMITED (JP) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165183-A1 PIPERIDINE DERIVATIVES AS JAK3 INHIBITORS JAK3, JAK2, JAK1 SRC 294/4885L3MBTL1 3775/4885TDP1 3985/4885
US-20120142617-A1 ANTIVIRAL THERAPEUTIC AGENTS EIF2AK2, ZC3HAV1, MAVS SRC 4196/4885L3MBTL1 2852/4885TDP1 1008/4885
US-20170362183-A1 PYRAZOLYL CARBOXYLIC ACID AND PYRAZOLYL UREA DERIVATIVE COMPOUNDS UROD, PEPD, CMPK1 SRC 3308/4885L3MBTL1 4741/4885TDP1 4301/4885
US-20230241257-A1 BIOTIN-MODIFIED DIMER AND USE THEREOF BTD, HLCS, BRD4 SRC 3321/4885L3MBTL1 362/4885TDP1 4134/4885
US-20130172341-A1 FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS MAPK1, MAPK3, MAP3K1 SRC 95/4885L3MBTL1 3893/4885TDP1 2565/4885
US-10035774-B2 Pyrazolyl carboxylic acid and pyrazolyl urea derivative compounds UROD, PEPD, CMPK1 SRC 3308/4885L3MBTL1 4741/4885TDP1 4301/4885
US-20110034517-A1 SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF ADRB2, ADRA2C, ADRA2A SRC 4109/4885L3MBTL1 3577/4885TDP1 3078/4885
US-20120022022-A1 NOVEL INHIBITORS OF CHYMASE CMA1, SERPINB1, TPSAB1 SRC 3180/4885L3MBTL1 4091/4885TDP1 1665/4885
US-20180193478-A1 ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE FOLR1, FOLR2, TUBB1 SRC 2609/4885L3MBTL1 3555/4885TDP1 1781/4885
US-20070249620-A1 Urea Derivative UGP2, SLC14A1, DGAT1 SRC 3906/4885L3MBTL1 1287/4885TDP1 4071/4885
US-20110105526-A1 SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF ADRB2, ADRA2C, ADRA2A SRC 3869/4885L3MBTL1 3428/4885TDP1 3329/4885
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS NOXO1, DDO, PTK2 SRC 707/4885L3MBTL1 4527/4885TDP1 729/4885
US-20170252458-A1 ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE FOLR1, FOLR2, TUBB1 SRC 2609/4885L3MBTL1 3555/4885TDP1 1781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.