SCHEMBL8736160

SCHEMBL8736160

CCCCCCCCCCCCCC(Cl)(Cl)C(=O)C(F)(F)F

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 7/20 0.66
EPHX1 P07099 1/20 0.48
FAAH O00519 12/20 0.48
CES1 P23141 9/20 0.48
MEN1 O00255 1/20 0.48
CYP1A2 P05177 1/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.48
LPAR1 Q92633 1/20 0.46
LPAR3 Q9UBY5 1/20 0.46
PLA2G6 O60733 1/20 0.42
FDPS P14324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7945509 0.83 CES2 (0.48) CES2FDPS
SCHEMBL24276176 0.78 CES2 (0.68) CES2EPHX1FAAHCES1MEN1
SCHEMBL8466412 0.77 SMPD1 (0.45) CES2MEN1KMT2AHSD17B10FDPS
SCHEMBL8464966 0.77 SMPD1 (0.45) CES2MEN1KMT2AHSD17B10FDPS
SCHEMBL7617795 0.77 SMPD1 (0.45) CES2MEN1KMT2AHSD17B10FDPS
SCHEMBL3284980 0.77 SMPD1 (0.45) CES2MEN1KMT2AHSD17B10FDPS
SCHEMBL658156 0.77 SMPD1 (0.45) CES2MEN1KMT2AHSD17B10FDPS
SCHEMBL7619946 0.77 SMPD1 (0.45) CES2MEN1KMT2AHSD17B10FDPS
SCHEMBL11197126 0.77 ALDH1A1 (0.48) CES2FDPS
SCHEMBL7623878 0.77 SMPD1 (0.45) CES2MEN1KMT2AHSD17B10FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872468-A1 Method for producing 3,3-dichloro-1,1,1-trifluoroacetone Central Glass Company, Limited (JP) 1998-10-21 EP claimed