SCHEMBL8736291

SCHEMBL8736291

CCCCCC(Cl)(Cl)C(=O)Cl

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
FDPS P14324 9/20 0.43
TP53 P04637 1/20 0.42
SMPD1 P17405 2/20 0.42
CES2 O00748 1/20 0.42
GGPS1 O95749 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11197126 0.98 ALDH1A1 (0.48) ALDH1A1TSHRFDPSSMPD1CES2
SCHEMBL11771263 0.98 ALDH1A1 (0.48) ALDH1A1TSHRFDPSSMPD1CES2
SCHEMBL11197128 0.93 ALDH1A1 (0.44) ALDH1A1TSHRFDPSTP53SMPD1
SCHEMBL11196231 0.82
SCHEMBL2207815 0.81 FDPS (0.43) ALDH1A1TSHRFDPSSMPD1CES2
SCHEMBL962102 0.80 FDPS (0.41) ALDH1A1TSHRFDPSSMPD1CES2
SCHEMBL15020977 0.80 TSHR (0.55) ALDH1A1TSHRTP53CES2
SCHEMBL10667625 0.79 FDPS (0.47) ALDH1A1TSHRFDPSSMPD1CES2
SCHEMBL3284980 0.79 SMPD1 (0.45) ALDH1A1TSHRFDPSSMPD1CES2
SCHEMBL658156 0.79 SMPD1 (0.45) ALDH1A1TSHRFDPSSMPD1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461268-B1 PROCESS FOR PRODUCING OLEFIN POLYMERIZATION CATALYST AND POLYOLEFIN IDEMITSU PETROCHEMICAL CO (JP) 1998-05-27 EP disclosed
US-5556820-A REACTION PRODUCT OF MAGNESIUM, ALCOHOL AND HALOGEN, SOLID IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-09-17 US disclosed
EP-0461268-A1 PROCESS FOR PRODUCING OLEFIN POLYMERIZATION CATALYST COMPONENT AND POLYOLEFIN IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-12-18 EP disclosed