Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736063 | 0.80 | CETP (0.49) | TDP1KDM4EALDH1A1HPGDCETP | |
| SCHEMBL8736604 | 0.77 | TDP1 (0.53) | TDP1KDM4EALDH1A1HPGDPTGDR2 | |
| SCHEMBL8733903 | 0.77 | PTGDR2 (0.40) | TDP1KDM4EALDH1A1HPGDCETP | |
| SCHEMBL8736524 | 0.77 | PTGDR2 (0.45) | TDP1KDM4EALDH1A1HPGDCETP | |
| SCHEMBL2649228 | 0.73 | PTGDR2 (0.66) | TDP1KDM4EALDH1A1HPGDPTGDR2 | |
| SCHEMBL27925883 | 0.72 | ALDH1A1 (0.68) | TDP1KDM4EALDH1A1HPGDPTGDR2 | |
| SCHEMBL2560912 | 0.71 | L3MBTL1 (0.67) | TDP1KDM4EALDH1A1HPGDPTGDR2 | |
| Naphthyloxyacetic Acid SCHEMBL8920389 | 0.70 | ALDH1A1 (0.79) | TDP1KDM4EALDH1A1HPGDPLA2G1B | |
| Naphthyloxyacetic Acid SCHEMBL29364154 | 0.70 | KDM4E (1.00) | TDP1KDM4EALDH1A1HPGDPTGDR2 | |
| Naphthyloxyacetic Acid SCHEMBL120838 | 0.70 | KDM4E (1.00) | TDP1KDM4EALDH1A1HPGDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | claimed |
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | claimed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | claimed |
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |