Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150877 | 0.91 | OPRM1 (0.33) | OPRM1TSHRTHRBGGPS1TRPM8 | |
| SCHEMBL28214778 | 0.88 | TSHR (0.38) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL5964919 | 0.88 | TSHR (0.38) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL20609969 | 0.83 | LMNA (0.30) | TSHR | |
| SCHEMBL11878349 | 0.83 | MMP8 (0.31) | — | |
| SCHEMBL20541317 | 0.76 | — | — | |
| SCHEMBL12058786 | 0.75 | OPRM1 (0.35) | OPRM1TSHRTHRBFDPS | |
| SCHEMBL24375706 | 0.74 | DNM1 (0.42) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL6063824 | 0.74 | TSHR (0.47) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL24459776 | 0.74 | OPRM1 (0.38) | OPRM1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461072-B1 | Process for the preparation of polyurethanes using specific stabilizer systems | CIBA GEIGY AG (CH) | 1998-07-29 | — | — | EP | disclosed |
| US-5077321-A | Using two structurally different stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0461072-A2 | Process for the preparation of polyurethanes using specific stabilizer systems | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |