SCHEMBL873750

SCHEMBL873750

O=c1c2ccccc2oc2cccc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 11/20 1.00
EGFR P00533 1/20 0.71
MGAM O43451 1/20 0.70
GAA P10253 1/20 0.70
SI P14410 1/20 0.70
MGAM2 Q2M2H8 1/20 0.70
KDM5A P29375 1/20 0.69
KDM4E B2RXH2 2/20 0.63
CYP3A4 P08684 2/20 0.63
MAPT P10636 2/20 0.63
HPGD P15428 2/20 0.63
HSD17B10 Q99714 2/20 0.63
ALDH1A1 P00352 1/20 0.63
GLA P06280 1/20 0.63
PGAM1 P18669 1/20 0.63
CASP1 P29466 1/20 0.63
CASP7 P55210 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
MEN1 O00255 1/20 0.56
USP2 O75604 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30346453 1.00 MAOA (1.00) MAOAEGFRMGAMGAASI
SCHEMBL30600021 1.00 MAOA (1.00) MAOAEGFRMGAMGAASI
SCHEMBL20346629 0.87 MAOA (0.76) MAOAEGFRMGAMGAASI
SCHEMBL20346606 0.86 MAOA (0.75) MAOAEGFRMGAMGAASI
SCHEMBL28683594 0.86 MAOA (0.74) MAOAEGFRMGAMGAASI
SCHEMBL30346466 0.86 MAOA (0.74) MAOAEGFRMGAMGAASI
SCHEMBL30241374 0.84 MAOA (0.71) MAOAEGFRMGAMGAASI
SCHEMBL329069 0.84 MAOA (0.71) MAOAEGFRMGAMGAASI
SCHEMBL15527312 0.83 MAOA (1.00) MAOAEGFRMGAMGAASI
SCHEMBL30738503 0.83 MAOA (1.00) MAOAEGFRMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107353275-B Synthesis method of xanthene-9-formic acid 常州市天华制药有限公司 2020-06-05 CN claimed
EP-3229756-B1 HAIR DYEING PROCESS USING AT LEAST ONE DYE, A TITANIUM SALT AND AN ANIONIC THICKENING POLYMER OREAL (FR) 2020-02-26 EP claimed
US-10524992-B2 Hair dyeing process using at least one direct and/or natural dye, a titanium salt, a cellulose-based polysaccharide and optionally a particular organic solvent L'OREAL (FR) 2020-01-07 US claimed
EP-3229755-B1 HAIR DYEING PROCESS USING AT LEAST ONE DIRECT AND/OR NATURAL DYE, A TITANIUM SALT, A CELLULOSE-BASED POLYSACCHARIDE AND OPTIONALLY A PARTICULAR ORGANIC SOLVENT OREAL (FR) 2019-06-12 EP claimed
EP-3229754-B1 HAIR DYEING PROCESS USING AT LEAST ONE DYE, A TITANIUM SALT AND AN INSOLUBLE SILICATE OREAL (FR) 2019-01-30 EP claimed
US-10052273-B2 Hair dyeing method employing at least one ortho-diphenol, one titanium derivative and one carboxylic acid L'OREAL (FR) 2018-08-21 US claimed
US-10010495-B2 Hair dyeing process using at least one ortho-diphenol and one organic salt of titanium and of a carboxylic acid L'OREAL (FR) 2018-07-03 US claimed
US-20170354584-A1 HAIR DYEING PROCESS USING AT LEAST ONE DYE, AN ORGANIC TITANIUM SALT, AND A NON-CELLULOSIC-BASED POLYSACCHARIDE L'OREAL (FR) 2017-12-14 US claimed
US-20170340542-A1 HAIR DYEING PROCESS USING AT LEAST ONE DYE, A TITANIUM SALT AND AN ANIONIC THICKENING POLYMER L'OREAL (FR) 2017-11-30 US claimed
US-20170333312-A1 HAIR DYEING PROCESS USING AT LEAST ONE DIRECT AND/OR NATURAL DYE, A TITANIUM SALT, A CELLULOSE-BASED POLYSACCHARIDE AND OPTIONALLY A PARTICULAR ORGANIC SOLVENT L'OREAL (FR) 2017-11-23 US claimed
US-20030103917-A1 Dyeing composition promoting natural pigmentation, method for obtaining same and use for colouring the skin and/or keratinous fibres L'OREAL (FR) 2003-06-05 US claimed
WO-2002076422-A1 USE OF A MIXTURE COMPRISING MN(II) AND/OR ZN(II) WITH A HYDROGENOCARBONATE AND AT LEAST AN ORTHODIPHENOL, AS AGENT REDUCING ADHESION OF MICRO-ORGANISMS L'OREAL (FR) 2002-10-03 WO claimed
US-20020124330-A1 Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres L'OREAL (FR) 2002-09-12 US claimed
EP-1229892-A1 DYEING COMPOSITION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES L'OREAL (FR) 2002-08-14 EP claimed
EP-1229890-A1 DYEING COMPOSITION PROMOTING NATURAL PIGMENTATION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES L'OREAL (FR) 2002-08-14 EP claimed
EP-1210931-A1 Keratinic fibres dyeing composition L'OREAL (FR) 2002-06-05 EP claimed
WO-2002030371-A1 DYEING COMPOSITION PROMOTING NATURAL PIGMENTATION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES L"OREAL (FR) 2002-04-18 WO claimed
WO-2002030375-A1 DYEING COMPOSITION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES L"OREAL (FR) 2002-04-18 WO claimed
EP-0473411-A1 Xanthenylamide handle for use in peptide synthesis and methods of producing said handle and support incorporating it REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1992-03-04 EP claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10524992-B2 Hair dyeing process using at least one direct and/or natural dye, a titanium salt, a cellulose-based polysaccharide and optionally a particular organic solvent KRT18, CD44, TYR MAOA 467/4885EGFR 656/4885MGAM 1923/4885
US-20030103917-A1 Dyeing composition promoting natural pigmentation, method for obtaining same and use for colouring the skin and/or keratinous fibres TYR, KRT18, POLR1C MAOA 259/4885EGFR 2700/4885MGAM 330/4885
US-10052273-B2 Hair dyeing method employing at least one ortho-diphenol, one titanium derivative and one carboxylic acid TYR, KRT18, DSG1 MAOA 502/4885EGFR 357/4885MGAM 4462/4885
US-10010495-B2 Hair dyeing process using at least one ortho-diphenol and one organic salt of titanium and of a carboxylic acid KRT18, TYR, DSG1 MAOA 365/4885EGFR 486/4885MGAM 4646/4885
US-20020124330-A1 Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres KRT18, TYR, OAT MAOA 232/4885EGFR 1670/4885MGAM 2059/4885
US-20170333312-A1 HAIR DYEING PROCESS USING AT LEAST ONE DIRECT AND/OR NATURAL DYE, A TITANIUM SALT, A CELLULOSE-BASED POLYSACCHARIDE AND OPTIONALLY A PARTICULAR ORGANIC SOLVENT KRT18, CD44, TYR MAOA 467/4885EGFR 656/4885MGAM 1923/4885
US-20170340542-A1 HAIR DYEING PROCESS USING AT LEAST ONE DYE, A TITANIUM SALT AND AN ANIONIC THICKENING POLYMER KRT18, TUBB1, DSG1 MAOA 70/4885EGFR 599/4885MGAM 3337/4885
US-20170354584-A1 HAIR DYEING PROCESS USING AT LEAST ONE DYE, AN ORGANIC TITANIUM SALT, AND A NON-CELLULOSIC-BASED POLYSACCHARIDE KRT18, CD44, DSG1 MAOA 246/4885EGFR 1353/4885MGAM 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.